It's hard not to love BMW's turbo sixes, and the M5 dazzles with its rev-matching manual.
While we prefer its coupe-like A7 cousin, the fine Audi A6 can be equipped with front- or all-wheel drive, a supercharged V-6, S-line sport trim, and a host of tech features.
The recently redesigned Cadillac CTS boasts outstanding style, improved rear-seat room, and excellent interior quality.
The Infiniti Q70 is an obvious alternative to the GS, with great handling, style and V-6 power, but suffers from a coarse engine note—further, in this group, the Infiniti badge may not have enough cachet for some buyers.
Finally, there's a new E-Class emerging for 2017—but the outgoing model still excels in big-car handling and in the sheer breadth of its offerings.
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 2016 Lexus GSBrowse Used Listings |  2016 Audi A6Browse Used Listings |  2016 BMW 5-SeriesBrowse Used Listings |  2016 Cadillac CTSBrowse Used Listings |  2016 INFINITI Q70Browse Used Listings |  2016 Mercedes-Benz E ClassBrowse Used Listings |
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| Quick Specs | |||||
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The 2016 Lexus GS F rivals the Germans for top-level handling, but hybrids and the turbo-four GS 200t pack fewer thrills. |
The 2016 Audi A6 builds on an already impressive set of features, abilities, and styling to yield a safe, fun, high-tech luxury sedan. |
The 2016 BMW M5 is the king of the 5-Series mountain, which isn't a bad place to be. It just may not be king of the sports sedan mountain anymore. |
The 2016 Cadillac CTS sedan is a stunning luxury sedan that drives as well or better than its European rivals. |
The 2016 Infiniti Q70—especially in its long-wheelbase form—poses an interesting alternative to conservative German luxury sedans. |
The 2016 Mercedes-Benz E-Class offers elegant comfort and luxury in several flavors, with a thrifty diesel and a high-performance V-8 for those at either end of the spectrum. |
| MSRP From | |||||
| $45,615 | $46,200 | $50,200 | $45,560 | $49,850 | $52,650 |
| Gas Mileage | |||||
| 16 MPG City / 34 MPG Hwy | 18 MPG City / 38 MPG Hwy | 14 MPG City / 38 MPG Hwy | 14 MPG City / 31 MPG Hwy | 16 MPG City / 34 MPG Hwy | 15 MPG City / 42 MPG Hwy |
| Engine | |||||
| Intercooled Turbo Premium Unleaded I-4 | Intercooled Turbo Premium Unleaded I-4 | Intercooled Turbo Premium Unleaded I-4 | Turbocharged Gas I4 | Premium Unleaded V-6 | Twin Turbo Diesel I-4 |
| EPA Class | |||||
| Midsize Cars | Midsize Cars | Midsize Cars | Mid-Size | Midsize Cars | Midsize Cars |
| Style Name | |||||
| 4-Door Sedan F Sport RWD | 4-Door Sedan FrontTrak 2.0T Premium | 4-Door Sedan 528i RWD | 4-Door Sedan 2.0L Turbo RWD | 4-Door Sedan V6 RWD | 4-Door Sedan E 250 BlueTEC Sport RWD |
| Drivetrain | |||||
| Rear Wheel Drive | Front Wheel Drive | Rear Wheel Drive | Rear Wheel Drive | Rear Wheel Drive | Rear Wheel Drive |
| Passenger Capacity | |||||
| 5 | 5 | 5 | 5 | 5 | 5 |
| Passenger Doors | |||||
| N/A | N/A | N/A | N/A | N/A | N/A |
| Body Style | |||||
| Sedan | Sedan | Sedan | 4 Door Sedan | Sedan | Sedan |
| Transmission | |||||
| Automatic w/OD | Auto-Shift Manual w/OD | Automatic w/OD | Automatic | Automatic w/OD | Automatic w/OD |
| Detailed Spec Comparison | |||||
| 2016 Lexus GS vs. 2016 Audi A6 | 2016 Lexus GS vs. 2016 BMW 5-Series | 2016 Lexus GS vs. 2016 Cadillac CTS | 2016 Lexus GS vs. 2016 INFINITI Q70 | 2016 Lexus GS vs. 2016 Mercedes-Benz E Class | |
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