The Acura TLX reaches high, and there are plenty of good contenders.
The BMW 5-Series was updated for 2021 and includes a long roster of available powertrains—not just high-performance ones, either.
Same goes for the Mercedes-Benz E-Class, which now includes an off-road wagon.
The Cadillac CT5 is new and a little calmer, but a storm is coming for that.
The Audi A6 is a technophile’s dream, and it's available as a hot wagon.
The Volvo S60 may be a wallflower here, but it’s sharp and clean inside.
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 2021 Acura TLX#12 in Luxury Mid-Size Cars Get Your Price |  2021 Audi A6Get Your Price |  2021 BMW 5-SeriesGet Your Price |  2021 Cadillac CT5Get Your Price |  2021 Mercedes-Benz E Class#1 in Coupes Get Your Price |  2021 Volvo S60Get Your Price |
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| Quick Specs | |||||
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The 2021 Acura TLX plants its flag among premium mid-size sedans with a racy design, strong turbocharged engines, and improved dynamics. |
The 2021 Audi A6 mid-size luxury sedan or wagon is reserved but flexible in its powertrain offerings and body styles. | The 2021 BMW 5-Series pushes all the right buttons for mid-size luxury shoppers. And there are a lot of them. |
Made as a sedan, wagon, coupe, and convertible with four different powertrains, the 2021 Mercedes E-Class has wide appeal. |
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| MSRP From | |||||
| $37,500 | $54,900 | $54,200 | $36,995 | $54,250 | $38,950 |
| Gas Mileage | |||||
| 21 MPG City / 31 MPG Hwy | 15 MPG City / 31 MPG Hwy | 15 MPG City / 33 MPG Hwy | 18 MPG City / 32 MPG Hwy | 15 MPG City / 31 MPG Hwy | 21 MPG City / 34 MPG Hwy |
| Engine | |||||
| Turbo Premium Unleaded I-4 | Intercooled Turbo Gas/Electric I-4 | Intercooled Turbo Premium Unleaded I-4 | Turbocharged Gas I4 | Intercooled Turbo Premium Unleaded I-4 | Intercooled Turbo Premium Unleaded I-4 |
| EPA Class | |||||
| Compact Cars | Mid-Size Cars | Mid-Size Cars | Mid-Size | Mid-Size Cars | Compact Cars |
| Style Name | |||||
| FWD | Premium Plus 45 TFSI quattro | 530i Sedan | 4-Door Sedan Luxury | E 350 RWD Sedan | T5 FWD Momentum |
| Drivetrain | |||||
| Front Wheel Drive | All Wheel | Rear Wheel Drive | Rear Wheel Drive | Rear Wheel Drive | Front Wheel Drive |
| Passenger Capacity | |||||
| 5 | 5 | 5 | 5 | 5 | 5 |
| Passenger Doors | |||||
| N/A | N/A | N/A | N/A | N/A | N/A |
| Body Style | |||||
| Sedan | quattro Sedan | Sedan | Sedan | Sedan | Sedan |
| Transmission | |||||
| Automatic w/OD | Auto-Shift Manual w/OD | Automatic w/OD | Automatic | Automatic w/OD | Automatic w/OD |
| Detailed Spec Comparison | |||||
| 2021 Acura TLX vs. 2021 Audi A6 | 2021 Acura TLX vs. 2021 BMW 5-Series | 2021 Acura TLX vs. 2021 Cadillac CT5 | 2021 Acura TLX vs. 2021 Mercedes-Benz E Class | 2021 Acura TLX vs. 2021 Volvo S60 | |
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