The LS only earns big SUV-like fuel economy, despite its eight-speed automatic transmission and optional hybrid model. The car's ECO mode does encourage drivers to behave more responsibly behind the wheel, though. It meters fuel usage, and blinks rapidly when acceleration pushes the sedan into lower-economy modes.
According to the EPA's most recent figures, the LS 600h L hybrid earns a rating of 19 mpg city, 23 mpg highway, and 20 mpg combined—solid ratings for the class, but in our experience, somewhat difficult to replicate. It does attempt to coach drivers to economize with a more detailed display that shows hybrid-driving modes in the place of the tachometer, except when Sport mode is selected.
In base form, the Lexus LS 460 with rear-wheel drive is rated by the EPA at 16 miles per gallon city, 24 miles per gallon highway, for a combined rating of 19 mpg. That's for either the standard- or long-wheelbase edition, and they're figures close to those you'd earn in Toyota's Highlander. Adding all-wheel drive drops by one mile per gallon the highway gas mileage number and the combined rating.