The EPA rates the 2014 Nissan Quest at 19 mpg city, 25 mpg highway. That puts it more or less on par with the other minivans in the segment, especially since the Toyota Sienna no longer has a four-cylinder option. No hybrid or diesel editions of the Quest are currently planned.
The Quest rings in about average for highway fuel economy, though there are some vehicles in the segment that do much better. The Honda Odyssey earns 28 mpg on the highway in its most expensive, six-speed-automatic version; Chrysler's minivans get 25 mpg highway. However, for city mileage, the Quest is a leader. Its 19 miles per gallon on the city cycle equals the Sienna and the Odyssey, while Chrysler's minivans check in significantly lower.