Neither NHTSA (National Highway Traffic Safety Administration) nor the IIHS (Insurance Institute for Highway Safety) has crash-tested a CLS-Class Mercedes. However, the editors of TheCarConnection.com have rated the CLS highly, based on the Mercedes-Benz track record for good crash-test scores and the sedan's extensive list of safety equipment.
As Edmunds notes, "the 2010 Mercedes-Benz CLS-Class comes standard with antilock disc brakes, active front head restraints, stability control, side curtain and abdomen airbags at all outboard positions and a driver's knee airbag." Standard equipment also includes a Pre-Safe system that takes steering and braking data to predict accidents, and "automatically tightens up the seatbelts, closes the sunroof and positions the right front seat for optimum airbag protection." Kelley Blue Book also lists "an advanced electro-hydraulic braking system" as standard equipment.
Visibility is the biggest safety issue in the 2010 CLS. The "low roofline and high beltline" can "impair outward visibility," ForbesAutos says, while Car and Driver points out the high beltline "makes looking out of the car and around the various pillars like poking your head out of a trash can that's sitting in a jail cell."