There is no shortage of good safety equipment available for the 2008 Lexus GS 350 and the 2008 Lexus GS 460.
TheCarConnection.com found no crash-test data from the National Highway Traffic Safety Administration (NHTSA), but notes that the demanding Insurance Institute for Highway Safety (IIHS) gave the 2008 Lexus GS its highest rating of "good" in both front and side impact tests. The IIHS tests were performed on a 2006 model, but are considered applicable to both the 2008 Lexus GS 350 and 2008 Lexus GS 460.
Edmunds reports that the 2008 Lexus GS has "a total of 10 airbags, including front and rear seat-mounted side airbags, driver and front passenger knee airbags and full-length head curtain airbags...standard [2008 Lexus] GS 460 safety equipment includes antilock brakes with brake assist and stability and traction controls." Additional optional equipment includes "run-flat tires [and] Lexus Link communications."
Cars.com notes that in addition to a full complement of airbags, the 2008 Lexus GS's "optional pre-collision system incorporates active braking, which can trigger the brakes automatically under certain conditions...[an] advanced stability system anticipates instability or skidding before it occurs, monitors actual versus intended action, and helps correct problems using a mix of braking, throttle and steering control."
ConsumerGuide remarks that "all-around visibility is good despite moderately shallow side and rear windows," due to the fact that 2008 Lexus GS seats are "set fairly high."