NHTSA (National Highway Traffic Safety Administration), the agency of the federal government that rates vehicles for safety, hasn't at all crash-tested the Lexus LS—and it probably won't, as the LS is a relatively low-volume vehicle—but the IIHS (Insurance Institute for Highway Safety) has awarded the LS sedans a "good" rating for their front-impact protection systems.
Lexus outfits its top-end luxury sedan with a wealth of standard and optional safety features. On all LS sedans, standard features include front side airbags, dual front knee bags, full-length side-curtain bags, and active headrests. Rear-seat side airbags are available. Vehicle Dynamics Integrated Management (VDIM), an advanced version of electronic stability control, is standard, and it's integrated with traction control and anti-lock brakes.
Lexus now offers an Enform and Safety Connect system on subscription basis; the telematic systems notify Lexus if the vehicle is involved in an accident and summon emergency personnel automatically.
The Lexus LS also features a self-parking system that steers the vehicle into a parallel or row parking spot as the driver backs up; some will find it helpful and a safety aid, but to others it's a gimmick.