With two more cylinders and two more gears, there's not even that much of a difference in acceleration. The GS 460 can get to 60 mph in about 5.5 seconds, which is only a few tenths of a second faster than the GS 350. However, the GS 460 does have that quiet, refined character of the larger Lexus LS 460 flagship.
Most other attributes are as you'd find them in the GS 350. While the GS handles quite well and has impressive poise in tight corners, its steering isn't quite as delightful as we'd hope for in a sport sedan—it's just lacking road feel. Comfort is good, with excellent ride quality, a quiet cabin, and a excellent materials, but the one glaring flaw is cramped seating—headroom can be tight, especially for backseat occupants. The Adaptive Variable Suspension is one key feature difference; all GS 460s get it, and it might improve ride quality and handling with a full load or on rough roads.
There's not much of a difference in feature sets between the GS 460 and GS 350 either, with Bluetooth, power heated and ventilated front seats, and a seven-inch touch screen all included. Top high-tech options include a premium Mark Levinson audio system, a power rear sunshade, rain-sensing wipers, Intuitive Park Assist, and a pre-collision system with adaptive cruise control.
For more information on the GS 460, see our full review of the 2011 Lexus GS 350.