The mid-size Lexus GS 350 has six cylinders and rear-wheel or all-wheel drive, which pits it directly against some of the most popular luxury sedans on sale today.
The Infiniti M37 may be its most direct challenger: it has great handling, a charming fluid style and rippling V-6 power, but some coarse drivetrain noises and less badge equity than some other brands.
The Audi A6 is new this year, and in truth we prefer its sleeker hatchback A7 cousin, but the front- or all-wheel-drive sedan can be had with a supercharged V-6 and tech wonders like Google Earth mapping and S-line sport trim.
The Cadillac CTS gets the nod for distinctive American styling and a lineup that includes sedan, coupe, and wagon, as well as the power-crazy V-Series, but rear-seat room is tight and the interior's aren't quite as well-turned-out as some others.
Of the Germans remaining on our list, the E Class and 5-Series both have their pluses and minuses: we love the Benz diesel sedans and the AMG E63, and BMW's turbo sixes are swell, but the BMW electronic driving feel is just that, and the Mercedes styling language isn't exactly settled.
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|2013 Lexus GS 350Browse Used Listings||2013 Audi A6Browse Used Listings||2013 BMW 5-SeriesBrowse Used Listings||2013 Cadillac CTSBrowse Used Listings||2013 INFINITI M37Browse Used Listings||2013 Mercedes-Benz E ClassBrowse Used Listings|
|19 MPG City / 28 MPG Hwy||18 MPG City / 33 MPG Hwy||16 MPG City / 34 MPG Hwy||18 MPG City / 27 MPG Hwy||17 MPG City / 26 MPG Hwy||15 MPG City / 32 MPG Hwy|
|Gas V6||Turbocharged Gas I4||Turbocharged Gas I4||Gas V6||Gas V6||Gas V6|
|Mid-Size||Midsize Cars||Mid-Size||Subcompact Cars||Midsize Car||Midsize Cars|
|4-Door Sedan RWD||4-Door Sedan FrontTrak 2.0T Premium Plus||4-Door Sedan 528i RWD||2-Door Coupe RWD||37 4-Door Sedan RWD||4-Door Sedan E 350 Luxury RWD *Ltd Avail*|
|Rear Wheel Drive||Front Wheel Drive||Rear Wheel Drive||Rear Wheel Drive||Rear-Wheel Drive||Rear Wheel Drive|
|Sedan||Sedan||Sedan||2 Door Coupe||4-Door Sedan||Sedan|
|Automatic w/Manual Shift||Continuously Variable Ratio||Automatic w/Manual Shift||Automatic||Automatic||Automatic w/Manual Shift|
|Detailed Spec Comparison|
|2013 Lexus GS 350 vs. 2013 Audi A6||2013 Lexus GS 350 vs. 2013 BMW 5-Series||2013 Lexus GS 350 vs. 2013 Cadillac CTS||2013 Lexus GS 350 vs. 2013 INFINITI M37||2013 Lexus GS 350 vs. 2013 Mercedes-Benz E Class|