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2010 Lexus GS 350 vs. Its Competition

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Our expert editors build comparisons like this one to make it easy for you to understand the small handful of cars you should compare to whatever car you are already looking at. You get general thoughts on each car you should consider plus an easy way to compare basic information for yourself.
2010 Lexus GS 350 4-door Sedan RWD Angular Front Exterior View
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TCC Rating
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There’s little doubt that the BMW 5-Series is one of the top rivals that Lexus has in mind with the GS sedans.

The 2010 5-Series is also very tech-focused, and it's now more comfort-oriented than it’s been in the past, though a new 5-Series is on the way for 2011.

Infiniti's M sedans, the M35 and M45, are actually its closest rivals in execution.

Compared to the GS, the M35/45 has a roomier interior but a similar sporty driving feel, with powerful engines and electronic driving aids, although interior noise is a bigger issue on the M than any of these rivals.

Cadillac’s CTS is a little bit smaller and more performance-focused, with excellent handling and performance, as well as a unique interior style.

The Lexus GS models also come across as more performance-oriented than the A6, lining up more closely with the 340-horsepower, V-8-powered S6, which takes on the GS 460.

But the S6 has all-wheel drive, a feature that's not available on the GS 460 (only the 350).

The Mercedes-Benz E-Class, recently redesigned, is softer and more comfort-oriented than the 2010 GS.

For the 2010 Lexus GS 450h, its leading rival is likely the Mercedes-Benz E320 BlueTec.

With a clean-diesel engine, the BlueTec gets much better fuel economy than the 450h, and it’s the more fitting choice for long-haul highway driving.

2010 Lexus GS 350 4-door Sedan RWD Angular Front Exterior View2010 Lexus GS 3502010 Audi S6 4-door Sedan Prestige Angular Front Exterior View2010 Audi S62010 BMW 5-Series Sports Wagon2010 BMW 5-Series2010 Cadillac CTS Sport Wagon2010 Cadillac CTS2010 Infiniti M2010 INFINITI M352010 Mercedes-Benz E-Class2010 Mercedes-Benz E Class
Quick Specs
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TCC Rating
Respectable performance and top technology make the 2010 Lexus GS 350 and GS 460 worthwhile sport sedans, but low points include a cramped backseat and a GS 450h hybrid model that fails to wow for fuel economy.
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TCC Rating
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TCC Rating
Whether as a sedan or wagon, the 2010 BMW 5-Series is a distinctly sportier, tech-savvy alternative to luxury rivals-without giving up any comfort.
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TCC Rating
The 2010 Cadillac CTS takes an edgy, American approach to European performance-and style, with the stunning CTS Sport Wagon.
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TCC Rating
The 2010 Infiniti M sedans reward drivers with Germanic handling and acceleration, though it's hard to pick them out from a crowd.
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TCC Rating
The 2010 Mercedes-Benz E-Class sedan swings to the masculine side of the pendulum and sharpens its driving appeal in the process.
MSRP From     
$45,600Browse Used Listings$76,100Browse Used Listings$45,950Browse Used Listings$35,165Browse Used Listings$45,800Browse Used Listings$48,050Browse Used Listings
Gas Mileage     
18 MPG City / 26 MPG Hwy14 MPG City / 19 MPG Hwy15 MPG City / 28 MPG Hwy16 MPG City / 27 MPG Hwy16 MPG City / 25 MPG Hwy13 MPG City / 26 MPG Hwy
Gas V6Gas V10Gas I6Gas V6Gas V6Gas V6
EPA Class     
Mid-SizeMidsizeMid-SizeMid-Size4-door Large CarSub-Compact
Style Name     
4-Door Sedan RWD4-Door Sedan Prestige4-Door Sedan 528i RWD4-Door Sedan 3.0L RWD35 4-Door Sedan RWD2-Door Coupe E350 RWD
Rear Wheel DriveAll-Wheel DriveRear Wheel DriveRear Wheel DriveRear-Wheel DriveRear Wheel Drive
Passenger Capacity     
Passenger Doors     
Body Style     
4 Door Sedan4 Door Sedan4 Door Sedan4 Door Sedan4-door Sedan2 Door Coupe
Automatic w/ODAutomaticManualManualAutomaticAutomatic w/OD
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